HEYDE’S SYNDROME: A CASE REPORT
Keywords:
Heyde’s syndrome, von Willebrand factor, diagnosisAbstract
Heyde syndrome is a multisystem disorder characterized by the classical triad of aortic stenosis,
gastrointestinal (GI) angiodysplasias, and acquired von Willebrand syndrome. GI
angiodysplasias, common in older patients, are tortuous, thin walled blood vessels seen in the
mucosa or submucosa of the GI tract and are highly prone to rupture resulting in GI bleeds.
We report a case of a 60-year-old woman with recurrent gastrointestinal bleeding and aortic
valve stenosis presented with bleeding from intestinal angiodysplasia, the exploration of von
willebrand factor revealed willebrand disease 2A, the patient was diagnosed with Heyde’s
syndrome.
We report throw a case of Heyde syndrome the role of hematology laboratory in the diagnostic
of this rare pathology.








