A MATHEMATICAL PROBABILITY MODEL USING FOR THE FLUVOXAMINE REDUCES RESPONSIVENESS OF HPA AXIS IN ADULT FEMALE BPD PATIENTS WITH A HISTORY OF SUSTAINED CHILDHOOD ABUSE

Abstract

The Weibull Generalized family of distributions was used to propose a three-parameter probability model
Weibull exponential distribution. The proposed model's mathematical property was discussed. The aim of this
study was to see how much ACTH and Cortisol secreted in response to the CRH/DEX test before, during, and
after 6 and 12 weeks of fluvoxamine treatment in female borderline patients with and without history of
sustained childhood abuse. For the two hormones described above, we plotted the cumulative distribution
function, probability vacuity function, failure rate, and responsibility function of the proposed model. We
discovered that BPD patients with a history of prolonged childhood abuse have the greatest reduction in ACTH
and cortisol, and that fluvoxamine therapy decreases the hyper responsiveness of the HPA axis. Finally, we
conclude that the proposed model's responsibility feature is well matched to the application component, and the
conclusion is compared to a medical study. This paper would be extremely helpful in the fields of insurance,
engineering, and medicine, as well as economics and finance.