A SHORT REVIEW ON CENTRAL DOGMA OF MOLECULAR BIOLOGY

Abstract

Francis Crick announced the Central Dogma of molecular biology upwards of half a century
(1958) to clarify the interconnections between the fundamental informational macromolecules,
including DNA, RNA, and proteins. This dogma asserted that genetic information could be
transferred from DNA to DNA/RNA or nucleic acid to protein. Nevertheless, transmitting
information from one protein to another or from one protein to nucleic acid is difficult. The
purpose of this essay is to assess Central Dogma's Basic concept.