FORMULATION AND EVALUATION OF MICROCAPSULES OF FURAZOLIDONE

Abstract

The objective of the present study was to develop Furazolidone prolonged release microcapsules by solvent evaporation method. This sustained release of microcapsules is additionally influenced by the formulation of latest biodegradable polymer HPMC and Ethyl cellulose, hence drug release pattern. The ready microcapsules were subjected to numerous pre and post formulation studies. Prepared microcapsules were evaluated for the particle size, percentage yield, entrapment efficiency, wall thickness, estimation of drug content and in vitro drug release studies. Results of the present study indicate that Furazolidone microcapsules can be successfully designed to develop sustained drug delivery, that reduces the dosing frequency and their by we can increase the patient compliance.