OUTBREAK OF ESBL-PRODUCING ENTEROBACTER CLOACAE IN NEONATAL UNITS: ABOUT 7 CASES.

Abstract

Background: Enterobacter cloacae species is responsible for nosocomial outbreaks in
vulnerable patients in neonatal intensive care units (NICU). The environment can constitute
the reservoir and source of infection in NICUs.
The aim of the present study was to describe the epidemiological and bacteriological aspects
of an outbreak of ESBL-producing Enterobacter cloacae in the neonatology unit of the
Mohammed VI University Hospital of Marrakech.
Materials and Methods: We reported seven cases of ESBL-producing Enterobacter cloacae
infections in neonates hospitalized in a neonatal unit over a period of two weeks, diagnosed
by microbiological study of the different cultural, morphological and biochemical
characteristics, as well as by the study of the germ's sensitivity to antibiotics
Results: The presence of ESBL was retained in front of an antibiogram showing a resistance
to all the betalactamins except carbapenems, as well as a synergy between the disks of C3G,
C4G and clavulanic acid, the resistance to the betalactamins was associated with that of the
tested fluoroquinolones in particular Ciprofloxacin and Norfloxacin and to the
aminoglycosides except amikacin as well as the resistance to the co-trimoxazole.
Conclusion: The emergence of multi-resistant bacteria with a high epidemic risk in our
hospital implies, Hence the interest in developing rapid and efficient means of identification
in order to limit their spread