REVIEW OF MECHANISM OF OSSIFICATION IN HUMAN BEINGS

Abstract

The process of ossification leads to the formation of the bony skeleton in embryos. In later life,
another form of ossification occurs until early adulthood. Fibrous membranes and hyaline
cartilage forms the embryonic skeleton before week 8 of gestation. After that, bony tissue begins
to develop and eventually replaces most of the existing fibrous or cartilage structures. There are
two types of Mechanisms of ossification, Endochondral Ossification and Intramembranous
Ossification. In endochondral ossification, hyaline cartilage is used for bone construction. While
in Intramembranous ossification begins within fibrous connective tissue membranes formed by
mesenchymal cells.